What are the peripheral blood smear clues for myelodysplastic syndrome? - myelodysplastic syndrome blogurl:blogspot.com
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Monday, February 1, 2010
Myelodysplastic Syndrome Blogurl:blogspot.com What Are The Peripheral Blood Smear Clues For Myelodysplastic Syndrome?
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Since MDS is a disorder of myeloid stem cells, there are often changes in the three cell lines PN smear. The seal is macrocytic red blood cells, with the second population of hypochromic and coarsely punctate. Howell basophilic stippling, Jolly, immature white blood cells which are / is not normally in use, with Pelger Huet annular bilobed nuclei, reduction or absence of cytoplasmic granules, abnormal platelet count, the movement of plates or poorly crystallized fragment of megakaryocytes was found. Abnormalities in more than one cell are very suggestive of MDS, especially in the absence of the explosion in the peripheral circulation.
ReplyDeleteErythrocytes: macrocytosis, anisocytosis, basophilic points to snatch cells
ReplyDeleteGB: hyposegmentation, pseudo-Pelger-Huet anomaly
Platelets: small, giant platelets
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